Brain Whole-genome Landscape

Explore gene-phenotype associations utilizing the most comprehensive UK Biobank brain imaging phenotype data

Study population and data

Population

Brain imaging cohort
Discovery
👥
(N=0)
Replication
👥
(N=0)

WGS data

Test tube with blood sample
DNA sequence visualization
Genotype
Variants
0
Genes
0
Fourteen functional masks
MissensePTVUpstreamDownstream5' UTR3' UTRSynonymousSpliceInframeIntronRNAPseudogenenctevIntergenic
+

Neuroimaging data

Structural MRI
Anatomical brain structure
Structural MRI
Diffusion MRI
White matter tracts
Diffusion MRI
SWI
Venous blood & iron
SWI
Functional MRI
Neural activity
Functional MRI

Whole-genome sequencing analysis

Single variant testing

0 lead SNP discovered
0 novel
Single variant testing plot
Brain image
Brain image
Brain image
Brain image

Gene-based testing

0 gene-phenotype pairs discovered
0 novel
Gene-based testing plot
Brain image
Brain image
Brain image
Brain image

Pleiotropy pattern

Pleiotropy pattern top row
Pleiotropy pattern bottom row

For details about the data source and analysis methods used, please refer to the associated publication. If you use any findings from this site, please cite the paper.

Yang L. et al. Mapping the genomic landscape of human brain structure and function.